
2022 AAP Hyperbilirubinemia Guidelines
What's new?
- Highlights the challenge of identifying G6PD deficiency in infants.
- Bases follow-up testing on the difference between bilirubin level and the phototherapy threshold. No more risk zones!
- Raises thresholds for phototherapy and exchange transfusion.
- Includes gestational age and risk factors for neurotoxicity in the thresholds.
- Adds when to check for rebound after stopping phototherapy.
- Offers how to provide intensive phototherapy and when home phototherapy is an option.
- Introduces “escalation of care” for serum bilirubin close to exchange transfusion level.
About Neurotoxicity Risk Factors
(updated May 2024)
- Selection of one or more of these risk factors (optional), including an elevated ETCOc (end-tidal carbon monoxide, corrected to ambient CO), will give guideline recommendations for the presence of neurotoxicity risk factors.
- Gestational age (required) automatically provides the appropriate recommendation from the AAP guideline.
