Newborn values:

—option one—

Birth date:

Date of birth is required

Birth time:

Time of birth is required

Sampling date:

Date of sampling is required

Sampling time:

Time of sampling is required

—option two—

Age (hours) at sampling:

or ,

Age of child at time of sampling must be between 1-336 hours (whole integer)

Total Bilirubin:

or ,

Total bilirubin (TSB or TcB), reported to a precision no more than tenths is required

Units:

Gestational age:

Gestational age in weeks is required

Other Neurotoxicity Risk Factors:

ETCOc

Isoimmune (or other) hemolytic disease or G6PD deficiency

Sepsis or clinical suspicion of sepsis

Albumin < 3.0 g/dL (30 g/L)

Significant clinical instability in the previous 24 hours

2022 AAP Hyperbilirubinemia Guidelines

What's new?

Highlights the challenge of identifying G6PD deficiency in infants.

Bases follow-up testing on the difference between bilirubin level and the phototherapy threshold. No more risk zones!

Raises thresholds for phototherapy and exchange transfusion.

Includes gestational age and risk factors for neurotoxicity in the thresholds.

Adds when to check for rebound after stopping phototherapy.

Offers how to provide intensive phototherapy and when home phototherapy is an option.

Introduces “escalation of care” for serum bilirubin close to exchange transfusion level.

About Neurotoxicity Risk Factors
(updated May 2024)

Selection of one or more of these risk factors (optional), including an elevated ETCOc (end-tidal carbon monoxide, corrected to ambient CO), will give guideline recommendations for the presence of neurotoxicity risk factors.

Gestational age (required) automatically provides the appropriate recommendation from the AAP guideline.